Purpose. To theoretically substantiate and develop agrobiological basics of sugar beet hybrids cultivation ensuring effective implementation of their breeding and genetic potential under the conditions of the Central Forest-Steppe of Ukraine. Methods. Field, laboratory and statistical. Results. Analysis of yield of sugar beet hybrids grown in Tetiiv region showed that the value of heterosis during 2007–2010 manifested differently in diploid and triploid hybrids. For example, hybrid ‘Ukrainskyi CMS 70’ had the root yield of 27.9 t/ha, the sugar content of 14.4%, sugar yield of 4.02 t/ha, that was less by 3.7 t/ha, 0.7%, and 0.78 t/ha, respectively, than in triploid hybrid Shevchenkivskyi. According to the research, the most productive hybrid appeared to be Shevchenkivskyi, whose average yield was 4.32 t/ha, sugar content 15.5 %, sugar yield 6.7 t/ha. Hybrids ‘Bilotserkivskyi CMS 57’ and ‘Ukrainskyi CMS 72’ had these figures virtually identical, but smaller as compared to the hybrid ‘Shevchenkivskyi’. ‘Shevchenkivskyi’ was found to have the highest plasticity having responded positively to improving growing conditions and created an increase in yield. Conclusion. On the average for three years, in the area of research farm Shevchenkivske, triploid hybrid 'Shevchenkivskyi showed the highest value of heterosis, namely root yield of 43.2 t/ha, the sugar content of 15.5 %, sugar yield of 6.7 t/ha. The highest root yield was marked in 2006 (56.5–63.1 t/ha) for hydrothermic coefficient HTC = 1.2 during growing season; the highest sugar content in 2008 (15.4–16.0%) for the HTC = 1.1.